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Clopidogrel, unlike prasugrel, was issued a black box warning from the FDA on March 12,. "FDA Announces New Boxed Warning on Plavix: Alerts patients,.

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PRODUCT MONOGRAPH Pr PLAVIX® Clopidogrel Tablets,. (PPI): Omeprazole, a moderate CYP2C19 inhibitor, reduces the pharmacological activity of PLAVIX.

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